I love YouTube. If you type in 'Stoicism' what do you get? An articulate transsexual called Sophia (appropriate that, it means Wisdom in Greek) giving a talk on how she uses Stoicism as a coping mechanism for dealing with life.
She knows her stuff: she describes Stoicism very accurately, and talks about how learning to shrug Stoically at people's disapproval has helped her survive as a transsexual living in the Bible Belt.
There is, in fact, a tradition of transsexual Stoicism - the philosophy to some extent emerged from Sophoclean tragedy, and the fount of all wisdom in Sophocles' Oedipus Tyrannus is...a transsexual, Tiresisas.